"Targeted Protein Degradation"
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08:00 |
08:20 |
Registration |
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08:20 |
08:30 |
Welcome by the Chairman of ELRIG.de e.V. |
Tobias May |
ELRIG.de e.V. |
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08:30 |
09:00 |
Clues to Molecular Glues |
Felix Hausch |
TU Darmstadt-Structure-Based Drug Research |
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09:00 |
09:30 |
Characterisation of glue degrader ternary complex dynamics and their effect on target degradation |
Grasilda Zenkeviciute |
Proxygen, Wien |
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09:30 |
10:00 |
Tracking the PROTAC degradation pathway in living cells highlights the importance of ternary complex measurement for PROTAC optimization |
Martin Schwalm |
Inst. f. Biochemie, Goethe Uni Frankfurt |
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10:00 |
10:30 |
Licence to eliminate – degraders at Merck |
Carola Sparn |
Merck KGaA, Darmstadt |
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10:30 |
11:00 |
Coffee break & Postersession |
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11:00 |
11:30 |
Deep proteomic screening for systematic discovery of degrader targets and mechanisms |
Henrik Daub |
NEOsphere, München |
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11:30 |
12:00 |
A novel E3-ligase-dependent glue degrader targeting STING |
Benedikt Goretzki |
Novartis, Basel |
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12:00 |
13:45 |
Lunch Break & Poster Session |
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13:45 |
14:15 |
Measurement of PROTAC ternary complex formation using the switchSENSE® Y-structure and FRET signals |
Ralf Strasser |
Dynamic Biosensors GmbH, München |
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14:15 |
14:45 |
Applying a „first principle“ biophysical method for Targeted Protein degradation |
Hedeby Hasse |
Fida Biosystems, Herlev, Dänemark |
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14:45 |
15:15 |
Mass photometry – an analytical technology for biomolecular characterization |
Tomás de Garay |
Refeyn Ltd., Oxford, UK |
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15:15 |
15:45 |
PRISKA: Integrated screening- and knowledge-platform for molecular degrader discovery |
Johanna Huchting |
ITMP Fraunhofer Hamburg |
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15:45 |
16:15 |
Enabling effective data management for PROTAC development |
Emilia Hietala |
Collaborative Drug Design, UK |
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16:15 |
16:45 |
Coffee break & Postersession |
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16:45 |
17:15 |
Deconvoluting the drivers of targeted protein degradation |
Kristin Riching |
Promega, USA |
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17:15 |
17:25 |
Snapshot: Simple Western with Jess is even more simple with CyBio FeliX Liquid Handling |
Christoph Heddergott |
Analytik Jena GmbH, Jena |
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17:25 |
17:30 |
Wrap up Forum 2023 |
Axel Johann |
Promega, Walldorf
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