Holger Saal, KyooBe, Leinfelden-Echterdingen

A new area in medicine–cell therapies–show promising patient outcomes but still lack commercial success and market access. Why? Most current approaches face challenges in bridging the gap between early clinical trials and efficient large-scale production. In this talk, we present MOSAIC, a novel manufacturing system developed by KyooBe Tech. The aim of MOSAIC is to overcome these challenges by combining modularity, scalability, and parallelization. MOSAIC consists of separate aseptic boxes that can culture cells for different patients and products simultaneously while allowing for both scale-out and scale-up strategies. We describe the design and functionality of MOSAIC and demonstrate its potential for cell therapy development and commercialization.