Proteomics for target and pathway deconvolution

Hannes Hahne, OmicScouts Preclinical stages in the drug discovery process require a multitude of biochemical and genetic assays in order to characterize the effects of drug candidates on cellular systems and model organisms. The identification and...

Deep proteomic screening for systematic discovery of degrader targets and mechanisms

of novel molecular glues and their cellular degradation targets has so far been challenging. Here, we introduce our deep proteomics screening and validation platform to initiate and advance TPD drug discovery programs. Deep proteomic screening is a mass...

ProxiCapture: A Platform for the Discovery of CRBN Binders via MS-Based Protein Interaction Profiling

Dr. Thorsten Mosler, Leader Proximity Proteomics, Uni Frankfurt Molecular glue degraders represent a rapidly expanding class of small molecules that reprogram E3 ubiquitin ligases to ubiquitinate and degrade disease-relevant proteins. Despite their...

ELRIG-Forum 2026 Programm

Small Molecules and Biologics – from Lab to Data 08:00 08:45 Registration 08:50 09:00 Welcome by the ELRIG.de e.V. Richard Rösch 09:00 09:40 Targeted protein degradation & protein proximity – a journey from high throughput screening to developing drugs...

2026

Enabling effective data management for PROTAC development

Additionally, the major analysis of PROTAC-induced degradation is marked by endpoint assays like Western blotting or proteomics, which throughput and dynamic range limit the analysis of PROTAC SAR series. To tackle this, we developed an assay pipeline...

Tracking the PROTAC degradation pathway in living cells highlights the importance of ternary complex measurement for PROTAC optimization

Additionally, the major analysis of PROTAC-induced degradation is marked by endpoint assays like Western blotting or proteomics, which throughput and dynamic range limit the analysis of PROTAC SAR series. To tackle this, we developed an assay pipeline...

Formulatrix

to the top pharmaceutical companies and leading academic research institutions working in a variety of genomics and proteomics applications. We are committed to researchers, labs, and to the scientific discoveries that will improve the lives of...