Georg Fertig, PhD, Head of Dept. Lead Identification, Large Molecule Research
Roche Pharma Research and Early Development (pRED)
Roche Innovation Center Munich, Germany
The generation of bi-functional bispecific antibodies requires the combination of two monospecific binders, which bind to the right epitope of the respective target in the right format. High-throughput generation and screening of such antibodies will be discussed in the context of an effective and robust technology platform an automated production of bsAb binder-format combination matrices the format, which defines the function.